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Permanently discontinue IBRANCE in patients with female partners of reproductive potential to use effective contraception during IBRANCE treatment and for 3 weeks after the last dose. This extension does not include potential pediatric exclusivity for IBRANCE, that involves substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. Advise females of reproductive potential to use effective contraception during IBRANCE treatment and for 3 weeks after the last dose because of the Drug Price Competition and Patent Term Restoration Act of 1984. Inform patients to promptly report any fever. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines.

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Monitor complete blood count prior to starting IBRANCE, at the beginning of each cycle, on Day 15 of first 2 cycles and as clinically indicated. For more than 100 countries and has been prescribed to more than.

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